Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 11/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491264 | 0.84 | LTB4R (0.58) | LTB4RCYSLTR2CYSLTR1PTPN11 | |
| SCHEMBL9496031 | 0.83 | LTB4R (0.63) | LTB4RMAPK1ALOX5TP53CYP1A2 | |
| SCHEMBL9490863 | 0.82 | LTB4R (0.64) | LTB4RMAPK1ALOX5TP53CYP1A2 | |
| SCHEMBL9493040 | 0.79 | LTB4R (0.67) | LTB4RMAPK1ALOX5TP53CYP1A2 | |
| SCHEMBL9496649 | 0.73 | LTB4R (0.41) | LTB4RMAPK1ALOX5TP53CYP1A2 | |
| SCHEMBL8663098 | 0.70 | MAPK1 (0.44) | LTB4RMAPK1ALOX5TP53CYP1A2 | |
| SCHEMBL9490956 | 0.69 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9494585 | 0.69 | LTB4R (0.64) | LTB4RPTPN11 | |
| SCHEMBL9494461 | 0.69 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9490796 | 0.69 | LTB4R (0.83) | LTB4RPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532634-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0532550-A1 | BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018880-A1 | BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991018879-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |