Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374070 | 0.92 | THRA (0.40) | NPC1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9373091 | 0.90 | MEN1 (0.38) | NPC1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9490430 | 0.89 | GPR84 (0.39) | NPC1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9490142 | 0.89 | GPR84 (0.39) | NPC1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9372611 | 0.88 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL9377057 | 0.87 | GPR84 (0.38) | NPC1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9374269 | 0.87 | PPARD (0.39) | MEN1KMT2AATML3MBTL1GPR84 | |
| SCHEMBL9488618 | 0.87 | POLB (0.41) | MEN1KMT2AATML3MBTL1CDK2 | |
| SCHEMBL9372058 | 0.87 | KMT2A (0.36) | NPC1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9757562 | 0.87 | HDAC3 (0.37) | NPC1MEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |