Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487903 | 0.95 | ADRB2 (0.50) | ADRB2ADRB1ADRB3LMNAMAPT | |
| SCHEMBL9488768 | 0.95 | TSHR (0.51) | ADRB2ADRB1ADRB3LMNAMAPT | |
| SCHEMBL9489466 | 0.93 | TSHR (0.52) | ADRB2ADRB1ADRB3LMNASMN1; SMN2 | |
| SCHEMBL9489062 | 0.92 | TSHR (0.54) | LMNASMN1; SMN2TSHRTP53NPC1 | |
| SCHEMBL9489432 | 0.92 | TSHR (0.54) | LMNASMN1; SMN2TSHRTP53NPC1 | |
| SCHEMBL9488466 | 0.92 | TSHR (0.54) | LMNASMN1; SMN2TSHRTP53NPC1 | |
| SCHEMBL9488761 | 0.92 | TSHR (0.54) | LMNASMN1; SMN2TSHRTP53NPC1 | |
| SCHEMBL9488693 | 0.91 | GAA (0.50) | ADRB2ADRB1ADRB3LMNAMAPT | |
| SCHEMBL9487517 | 0.91 | LMNA (0.50) | ADRB2ADRB1ADRB3LMNAMAPT | |
| SCHEMBL9488020 | 0.89 | LMNA (0.54) | LMNAMAPTALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | claimed |
| US-5236618-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4744918-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-05-17 | — | — | US | disclosed |
| EP-0168043-A2 | Liquid crystal phase | MERCK PATENT GmbH (DE) | 1986-01-15 | — | — | EP | disclosed |