Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485366 | 0.96 | RAB9A (0.36) | RAB9AACACBTSHRCRBNSCN8A | |
| SCHEMBL9485354 | 0.95 | THRB (0.35) | RAB9ACRBNSMN1; SMN2MAPTTHRB | |
| SCHEMBL9485173 | 0.95 | RAB9A (0.35) | RAB9AACACBCRBNSCN8ASCN10A | |
| SCHEMBL9433247 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT | |
| SCHEMBL9485498 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT | |
| SCHEMBL7501761 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT | |
| SCHEMBL9433251 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT | |
| SCHEMBL9658937 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT | |
| SCHEMBL9486093 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT | |
| SCHEMBL9485306 | 0.94 | THRB (0.37) | RAB9AKMT2ACRBNSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |