Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243271 | 0.87 | CHRM2 (0.59) | CHRM2TAAR1MAPT | |
| SCHEMBL8616255 | 0.84 | CHRM2 (0.73) | CHRM2SCN8A | |
| SCHEMBL10942286 | 0.81 | TAAR1 (0.56) | CHRM2TAAR1MAPT | |
| SCHEMBL20615042 | 0.79 | CHRM2 (0.52) | CHRM2TAAR1DRD2SIGMAR1MAPT | |
| SCHEMBL5248699 | 0.79 | TAAR1 (0.54) | CHRM2TAAR1MAPT | |
| SCHEMBL8096347 | 0.78 | SIGMAR1 (0.69) | CHRM2SIGMAR1 | |
| SCHEMBL9201570 | 0.78 | CHRM2 (0.50) | CHRM2TAAR1ALDH1A1MAPT | |
| SCHEMBL10865658 | 0.77 | TAAR1 (0.52) | CHRM2TAAR1MAPT | |
| SCHEMBL10725177 | 0.77 | TAAR1 (0.52) | CHRM2TAAR1MAPT | |
| SCHEMBL9650526 | 0.77 | TAAR1 (0.52) | CHRM2TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231003-B1 | BASIC SUBSTITUTED PHENYLACETONITRILES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-04-07 | — | — | EP | disclosed |
| EP-0231003-A2 | Basic substituted phenylacetonitriles, their preparation and medicaments containing them | BASF Aktiengesellschaft (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0147707-B1 | 1,7-DIPHENYL-3-METHYLAZA-7-CYANO-8-METHYLNONANE USEFUL IN COMBATING DISEASES | BASF Aktiengesellschaft (DE) | 1987-03-18 | — | — | EP | disclosed |
| EP-0147707-A2 | 1,7-Diphenyl-3-methylaza-7-cyano-8-methylnonane useful in combating diseases | BASF Aktiengesellschaft (DE) | 1985-07-10 | — | — | EP | disclosed |