Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654599 | 1.00 | ALDH1A1 (0.66) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL4654604 | 1.00 | ALDH1A1 (0.66) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL8463735 | 0.85 | ALDH1A1 (0.64) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL8875624 | 0.84 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL15304002 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL26671198 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL28326459 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL3022669 | 0.80 | ALDH1A1 (0.72) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL23780862 | 0.80 | ALDH1A1 (0.62) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL8064782 | 0.80 | ALDH1A1 (1.00) | ALDH1A1ADRB2ADRB1ADRB3PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250743-A | Reacting in acidic medium acyclic vinyl epoxide with water and/or alcohol to form inverted 1,2-dihydroxy-3-alkene or 1-hydroxy-2-alkoxy-3-alkene | EASTMAN KODAK COMPANY (US) | 1993-10-05 | — | — | US | disclosed |