Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491204 | 0.78 | XDH (0.43) | MAPTALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9208032 | 0.74 | CYP3A4 (0.47) | MAPTTDP1ALDH1A1KDM4EADRA2A | |
| SCHEMBL8953418 | 0.74 | KDM4E (0.50) | MAPTALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL7347858 | 0.73 | FLT3 (0.69) | MAPTCASP3SENP7TDP1ALDH1A1 | |
| SCHEMBL9493033 | 0.73 | BCL2L1 (0.47) | CASP3SENP7TDP1ALDH1A1HPGD | |
| SCHEMBL28107976 | 0.72 | MAPT (0.77) | MAPTCASP3SENP7TDP1ALDH1A1 | |
| SCHEMBL31619040 | 0.72 | MAPT (0.63) | MAPTCASP3SENP7TDP1ALDH1A1 | |
| SCHEMBL29023280 | 0.72 | FLT3 (0.67) | MAPTCASP3SENP7TDP1ALDH1A1 | |
| SCHEMBL10472882 | 0.71 | KDM4E (0.47) | MAPTALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL3529069 | 0.70 | MAPT (0.69) | MAPTCASP3SENP7TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180419-A | Herbicidal 2-(2-imidazolin-2-yl)-benzo-(5-membered)-heterocycles and the use thereof | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |