Protocatechuic Acid

Protocatechuic Acid

SCHEMBL9491440

O=C(O)c1ccc(O)c(O)c1.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.95
CA1 P00915 5/20 0.95
CA2 P00918 5/20 0.95
CA7 P43166 5/20 0.95
CA9 Q16790 5/20 0.95
CA14 Q9ULX7 5/20 0.95
KDM4E B2RXH2 3/20 0.95
CA4 P22748 3/20 0.95
CA6 P23280 3/20 0.95
MAPT P10636 2/20 0.95
GAA P10253 2/20 0.95
POLB P06746 1/20 0.95
PTGS2 P35354 1/20 0.95
L3MBTL1 Q9Y468 1/20 0.95
HDAC6 Q9UBN7 1/20 0.56
HTT P42858 1/20 0.55
TP53 P04637 2/20 0.54
CA3 P07451 2/20 0.54
CA5A P35218 2/20 0.54
CA5B Q9Y2D0 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Protocatechuic Acid SCHEMBL29005616 1.00 CA12 (0.95) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL39435 0.97 CA12 (1.00) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL30030432 0.97 CA12 (1.00) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL27815804 0.97 CA12 (1.00) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL29350008 0.97 CA12 (1.00) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL23495982 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL2274950 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL30767247 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL30677996 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
Protocatechuic Acid SCHEMBL28487427 0.95 CA12 (0.95) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4118079-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME Novartis AG (CH) 2023-01-18 EP claimed
CN-115279745-A Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using the same 诺华股份有限公司 2022-11-01 CN claimed
CN-114672068-A Intumescent flame retardant for polyurethane, flame-retardant polyurethane and preparation of flame-retardant polyurethane 四川大学 2022-06-28 CN claimed
WO-2021181361-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME NOVARTIS AG (CH) 2021-09-16 WO claimed
CN-113387923-A Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using the same 诺华股份有限公司 2021-09-14 CN claimed
CN-118099430-A Cathode for secondary battery and cathode slurry 广东省皓智科技有限公司 2024-05-28 CN disclosed
CN-114424365-B Cathode for secondary battery and cathode slurry 广东省皓智科技有限公司 2024-04-23 CN disclosed
CN-116019125-B Chlorine dioxide slow-release gel and preparation method thereof 山东华实药业有限公司 2023-05-23 CN disclosed
CN-116019125-A Chlorine dioxide slow-release gel and preparation method thereof 山东华实药业有限公司 2023-04-28 CN disclosed
US-11590158-B2 Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using same NOVARTIS AG (CH) 2023-02-28 US disclosed
EP-4118079-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME Novartis AG (CH) 2023-01-18 EP disclosed
CN-115279745-A Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using the same 诺华股份有限公司 2022-11-01 CN disclosed
CN-114424365-A Cathode for secondary battery and cathode slurry 广东省皓智科技有限公司 2022-04-29 CN disclosed
US-20210393671-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME NOVARTIS PHARMA AG (CH) 2021-12-23 US disclosed
US-11135239-B1 Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using same NOVARTIS AG (CH) 2021-10-05 US disclosed
WO-2021181361-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME NOVARTIS AG (CH) 2021-09-16 WO disclosed
US-20210283171-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME NOVARTIS PHARMA AG (CH) 2021-09-16 US disclosed
CN-113387923-A Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using the same 诺华股份有限公司 2021-09-14 CN disclosed
US-5189157-A ANTIBACTERIAL CEPHALOSPORIN COMPOUNDS HOFFMANN LA ROCHE INC. (US) 1993-02-23 US disclosed
US-5145946-A PROCESS FOR PREPARING POLYARYLENE SULFIDE WITH ALKALI METAL SALT OF PHENOLIC AROMATIC CARBOXYLIC ACID TOYO BOSEKI KABUSHIKI KAISHA (JP) 1992-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393671-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME LIPA, LIPC, LIPE CA12 222/4885CA1 270/4885CA2 260/4885
US-11135239-B1 Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using same LIPA, LIPC, LIPE CA12 222/4885CA1 270/4885CA2 260/4885
US-11590158-B2 Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using same LIPA, LIPC, LIPE CA12 222/4885CA1 270/4885CA2 260/4885
US-20210283171-A1 PHARMACEUTICAL COMPOSITIONS OF LIPOIC ACID CHOLINE ESTER SALTS AND METHODS OF TREATMENT USING SAME LIPA, LIPC, LIPE CA12 222/4885CA1 270/4885CA2 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.