SCHEMBL949187

SCHEMBL949187

CO[Si](CCCCCCC1CC2C=CC1C2)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 4/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.32
ALOX15 P16050 1/20 0.32
EPHX2 P34913 1/20 0.31
HTT P42858 1/20 0.31
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL949256 0.98 KDM4E (0.37) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL1477235 0.94 KDM4E (0.38) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL16335885 0.87 KDM4E (0.40) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL115037 0.87 KDM4E (0.40) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL6063400 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AEPHX2
SCHEMBL6064093 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AEPHX2
SCHEMBL6063639 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AEPHX2
SCHEMBL6062705 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AEPHX2
SCHEMBL6064189 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AEPHX2
SCHEMBL6062698 0.86 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875686-B2 comprising 10 to 99 wt. % of norbornene-type cycloolefin monomers; for microelectronic, optoelectronic and micro-optoelectronic applications such as die attach adhesives, underfill materials, prepreg binders, encapsulants PROMERUS LLC (US) 2011-01-25 US disclosed
EP-1791888-B1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS PROMERUS LLC (US) 2009-03-25 EP disclosed
EP-1791888-A1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS Promerus, LLC (US) 2007-06-06 EP disclosed
WO-2006023511-A1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS PROMERUS LLC (US) 2006-03-02 WO disclosed
US-20060041093-A1 Polycycloolefin polymeric compositions for semiconductor applications SUMITOMO BAKELITE CO., LTD. (JP) 2006-02-23 US disclosed