Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPOR | P19235 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491925 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2EPORALOX5 | |
| SCHEMBL9492638 | 0.89 | EPOR (0.58) | ALDH1A1EPORALOX5PTGS1PTGS2 | |
| SCHEMBL9492646 | 0.89 | EPOR (0.58) | ALDH1A1EPORALOX5PTGS1PTGS2 | |
| SCHEMBL9493790 | 0.80 | EPOR (0.48) | ALDH1A1HPGDSMN1; SMN2EPORALOX5 | |
| SCHEMBL9493775 | 0.80 | EPOR (0.48) | ALDH1A1HPGDSMN1; SMN2EPORALOX5 | |
| Hydrochloric Acid SCHEMBL9493052 | 0.78 | EPOR (0.46) | ALDH1A1HPGDSMN1; SMN2EPORALOX5 | |
| Hydrochloric Acid SCHEMBL9492580 | 0.78 | EPOR (0.46) | ALDH1A1HPGDSMN1; SMN2EPORALOX5 | |
| SCHEMBL23244710 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL2770484 | 0.77 | RELA (0.61) | RELA | |
| SCHEMBL11217503 | 0.77 | HPGD (0.55) | ALDH1A1HPGDSMN1; SMN2ALOX5TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279531-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF INSECTICIDALLY ACTIVE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-10 | — | — | EP | claimed |
| EP-0279531-A2 | Process and intermediates for the preparation of insecticidally active compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | claimed |
| EP-0279531-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF INSECTICIDALLY ACTIVE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-10 | — | — | EP | disclosed |
| US-5081273-A | PROCESS FOR THE PREPARATION OF INSECTICIDALLY ACTIVE DIPHENYL ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4942264-A | WITTIG REACTION FOLLOWED BY REDUCTION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-17 | — | — | US | disclosed |
| EP-0279531-A2 | Process and intermediates for the preparation of insecticidally active compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |