SCHEMBL94921

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17730097	0.86	HTT (0.69)	GAAMGLLMAPTHTTCA12
	SCHEMBL95918	0.86	HTT (0.69)	GAAHTTCA12CA1CA2
	SCHEMBL96162	0.85	HTT (0.52)	GAAMGLLMAPTHTTCA12
	SCHEMBL9138519	0.84	PRKAA2 (0.58)	GAAMGLLMAPTHTTCA12
	SCHEMBL94863	0.80	MGLL (0.86)	MGLLMAPTMEN1KMT2AHSD11B1
	SCHEMBL95512	0.80	HTR2B (0.52)	GAAMGLLMAPTHTTCA12
	SCHEMBL10719972	0.79	HTT (0.78)	GAAHTTCA12CA1CA2
	SCHEMBL4959434	0.79	ALDH1A1 (0.59)	MGLLMEN1KMT2AALDH1A1CCR3
	SCHEMBL9137879	0.78	GAA (0.53)	GAAMGLLMAPTHTTCA12
	SCHEMBL27924584	0.77	ALDH1A1 (0.54)	GAAALDH1A1CCR3CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.