Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949211 | 1.00 | S1PR1 (0.41) | S1PR1F2MIF | |
| SCHEMBL948658 | 0.84 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL948657 | 0.84 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL946678 | 0.83 | S1PR1 (0.45) | S1PR1F2MIF | |
| SCHEMBL948569 | 0.81 | NR1H2 (0.32) | — | |
| SCHEMBL948567 | 0.81 | NR1H2 (0.32) | — | |
| SCHEMBL3401067 | 0.73 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL3746518 | 0.73 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL948220 | 0.69 | S1PR1 (0.82) | S1PR1 | |
| SCHEMBL12277803 | 0.69 | PLA2G4A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005295-A1 | MODULATORS OF THE SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |