Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491471 | 0.89 | LTB4R (0.47) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL9491165 | 0.89 | LTB4R (0.47) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL9492158 | 0.84 | LTB4R (0.42) | LTB4R | |
| SCHEMBL9495931 | 0.83 | LTB4R (0.51) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL8081126 | 0.81 | MEN1 (0.57) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL8072236 | 0.81 | MEN1 (0.57) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL8081517 | 0.81 | MEN1 (0.57) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL8080247 | 0.81 | MEN1 (0.57) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL8081501 | 0.81 | MEN1 (0.57) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL10803242 | 0.81 | MEN1 (0.57) | PPARGPPARAPPARDLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532550-A1 | BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0532634-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018880-A1 | BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991018879-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |