Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.59 |
| ▸ | NQO2 | P16083 | 8/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884747 | 0.86 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL13048484 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL3410298 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL11403440 | 0.79 | MTNR1A (0.68) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8887234 | 0.79 | MTNR1A (0.87) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL23788244 | 0.78 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7104353 | 0.78 | MTNR1A (0.86) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7950130 | 0.78 | MTNR1A (0.86) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8885662 | 0.78 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL12394485 | 0.78 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |