Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecanoic Acid Amide SCHEMBL9492942 | 1.00 | SOAT1 (0.45) | SOAT1MEN1KMT2AFAAHTP53 | |
| 3-Octanone SCHEMBL28260918 | 0.84 | KMT2A (0.37) | MEN1KMT2ACES2CES1GPR84 | |
| Dodecanoate SCHEMBL28185346 | 0.80 | GPR84 (0.45) | MEN1KMT2ACYP1A2CYP2C19GPR84 | |
| Dodecanol SCHEMBL27739377 | 0.80 | LMNA (0.46) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| Octadecanoic Acid Amide SCHEMBL29044307 | 0.79 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL27549774 | 0.76 | SOAT1 (0.52) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL5975798 | 0.75 | SOAT1 (0.61) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL3984610 | 0.75 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Cyclohexane SCHEMBL2898947 | 0.75 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL9075014 | 0.75 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189190-A | Vicinal disubstituted carboxylic acids and silylated derivatives | HENKEL RESEARCH CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-4996342-A | Vicinal disubstituted carboxylic acids and silylated derivatives | HENKEL RESEARCH CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| WO-1990009366-A1 | VICINAL DISUBSTITUTED CARBOXYLIC ACIDS AND SILYLATED DERIVATIVES | HENKEL RESEARCH CORPORATION (US) | 1990-08-23 | — | — | WO | disclosed |