Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495931 | 0.82 | LTB4R (0.51) | LTB4RNPSR1CYSLTR2CYSLTR1 | |
| Octanedioate SCHEMBL30999498 | 0.81 | ALDH1A1 (0.67) | LTB4RNPSR1PTPN11MEN1NR1I2 | |
| SCHEMBL9490960 | 0.80 | LTB4R (0.70) | LTB4RPTPN11 | |
| SCHEMBL9490804 | 0.80 | LTB4R (0.58) | LTB4RNPSR1PTPN11MEN1NR1I2 | |
| SCHEMBL527254 | 0.79 | KMT2A (0.74) | NPSR1PTPN11MEN1NR1I2LMNA | |
| SCHEMBL3665313 | 0.79 | KMT2A (0.74) | NPSR1PTPN11MEN1NR1I2LMNA | |
| SCHEMBL18141371 | 0.79 | KMT2A (0.74) | NPSR1PTPN11MEN1NR1I2LMNA | |
| SCHEMBL1274781 | 0.79 | KMT2A (0.74) | NPSR1PTPN11MEN1NR1I2LMNA | |
| SCHEMBL112985 | 0.79 | KMT2A (0.74) | NPSR1PTPN11MEN1NR1I2LMNA | |
| SCHEMBL6575990 | 0.79 | KMT2A (0.74) | NPSR1PTPN11MEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532634-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | claimed |
| EP-0532550-A1 | BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | claimed |
| WO-1991018880-A1 | BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | claimed |
| WO-1991018879-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | claimed |