Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494198 | 0.90 | ALDH1A1 (0.44) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL9494204 | 0.90 | ALDH1A1 (0.44) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL9494778 | 0.88 | ALDH1A1 (0.42) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL9493430 | 0.88 | ALDH1A1 (0.42) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL9493434 | 0.88 | ALDH1A1 (0.42) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL9494771 | 0.88 | ALDH1A1 (0.42) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL28839597 | 0.78 | CES2 (0.52) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL16795665 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL16795666 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL28708574 | 0.77 | GAA (0.41) | ALDH1A1ALOX15CES2CES1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352956-B1 | PROCESS FOR THE PRODUCTION OF HALOBENZOPHENONE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4960945-A | Process for the production of halobenzophenone derivatives | KUREHA KAGAKU KOGYO K.K. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0352956-A1 | Process for the production of halobenzophenone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-31 | — | — | EP | disclosed |