Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374177 | 0.97 | EPHX2 (0.50) | EPHX2NR1H4LMNAHDAC8HDAC11 | |
| SCHEMBL10561346 | 0.87 | EPHX2 (0.57) | EPHX2NR1H4LMNAHDAC6HDAC3 | |
| SCHEMBL9806765 | 0.83 | KCNQ3 (0.60) | EPHX2NR1H4LMNAHDAC8HDAC11 | |
| SCHEMBL9479015 | 0.82 | EPHX2 (0.51) | EPHX2NR1H4LMNAHDAC8HDAC11 | |
| SCHEMBL8998273 | 0.81 | EPHX2 (0.66) | EPHX2NR1H4LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9479588 | 0.79 | LMNA (0.41) | EPHX2NR1H4LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9491290 | 0.78 | EPHX2 (0.55) | EPHX2NR1H4LMNAHDAC8HDAC11 | |
| SCHEMBL19083763 | 0.78 | EPHX2 (0.57) | EPHX2NR1H4LMNAHDAC8HDAC11 | |
| SCHEMBL9479068 | 0.77 | CNR1 (0.41) | EPHX2NR1H4LMNAHDAC8HDAC11 | |
| SCHEMBL9479575 | 0.77 | EPHX2 (0.49) | EPHX2NR1H4LMNAHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234942-A | Treating allergic pulmonary disorders, asthma | ICI AMERICAS INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-4997844-A | Compounds for the treatment of allergic or inflammatory diseases or shock conditions | ICI AMERICAS INC. (US) | 1991-03-05 | — | — | US | disclosed |