Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.60 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.60 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.60 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479618 | 0.86 | EPHX2 (0.58) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL9480375 | 0.85 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL9479236 | 0.84 | KCNQ3 (0.60) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL10374177 | 0.84 | EPHX2 (0.50) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL9493566 | 0.83 | EPHX2 (0.51) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL9479634 | 0.82 | LMNA (0.47) | KCNQ3KCNQ2KCNQ4KCNQ5SMN1; SMN2 | |
| SCHEMBL9478593 | 0.80 | LMNA (0.47) | KCNQ3KCNQ2KCNQ4KCNQ5HDAC3 | |
| SCHEMBL9806732 | 0.79 | ADA (0.58) | KCNQ3KCNQ2KCNQ4KCNQ5HDAC3 | |
| SCHEMBL9806769 | 0.79 | KCNQ3 (0.54) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL9479659 | 0.78 | HDAC3 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997844-A | Compounds for the treatment of allergic or inflammatory diseases or shock conditions | ICI AMERICAS INC. (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0179619-B1 | HETEROCYCLIC AMIDES | ICI AMERICAS INC. (US) | 1990-09-05 | — | — | EP | disclosed |