Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23053348 | 0.81 | LMNA (0.56) | AKR1C3AKR1C2ACACBMEN1KMT2A | |
| SCHEMBL2810556 | 0.81 | LMNA (0.56) | AKR1C3AKR1C2ACACBMEN1KMT2A | |
| SCHEMBL3672650 | 0.81 | AKR1C3 (0.71) | AKR1C3AKR1C2ACACBFPR2ALDH1A1 | |
| SCHEMBL271988 | 0.81 | SRC (0.78) | SRCAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL28846111 | 0.79 | AKR1C3 (0.50) | AKR1C3AKR1C2ACACBMEN1KMT2A | |
| SCHEMBL11686501 | 0.79 | SLC6A4 (0.50) | AKR1C3AKR1C2ACACBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11360245 | 0.76 | AKR1C3 (0.51) | AKR1C3AKR1C2ACACBMEN1KMT2A | |
| SCHEMBL11835319 | 0.76 | LMNA (0.50) | AKR1C3AKR1C2ACACBSLC6A4PLK1 | |
| SCHEMBL1624921 | 0.76 | SLC6A4 (0.52) | AKR1C3AKR1C2MEN1KMT2ASLC6A4 | |
| SCHEMBL11844893 | 0.75 | AKR1C3 (0.50) | AKR1C3AKR1C2ACACBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |