Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494024 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL9494748 | 0.82 | — | — | |
| SCHEMBL9494743 | 0.82 | — | — | |
| SCHEMBL10880739 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL10880745 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL10726048 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL10876986 | 0.80 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1RECQLMCL1 | |
| SCHEMBL9493724 | 0.80 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1RECQLMCL1 | |
| SCHEMBL9492364 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9492368 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | claimed |
| US-5177091-A | Rheumatic disorders | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |
| EP-0224515-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007360-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1986-12-18 | — | — | WO | disclosed |
| US-4582841-A | ANTITUMOR AND -CARCINOGENIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0085275-B1 | SUBSTITUTED THIAZOLIDINYLIC ESTERS OF MINERAL ACIDS | CIBA-GEIGY AG (CH) | 1986-02-19 | — | — | EP | disclosed |
| EP-0085275-A1 | Substituted thiazolidinylic esters of mineral acids | CIBA-GEIGY AG (CH) | 1983-08-10 | — | — | EP | disclosed |