Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684384 | 0.89 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9494024 | 0.81 | ALDH1A1 (0.33) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL9494018 | 0.81 | ALDH1A1 (0.33) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL9492364 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9492368 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9494748 | 0.76 | — | — | |
| SCHEMBL9494743 | 0.76 | — | — | |
| SCHEMBL10876986 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| Phosphoric Acid SCHEMBL10880246 | 0.75 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9493724 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224515-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007360-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1986-12-18 | — | — | WO | disclosed |