Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491579 | 0.91 | PARP1 (0.44) | DHODHKDM4EHPGDPARP1 | |
| SCHEMBL9491706 | 0.85 | DHODH (0.42) | DHODHKDM4EHPGDPARP1 | |
| SCHEMBL4119807 | 0.79 | DHODH (0.44) | DHODHPARP1 | |
| SCHEMBL9492712 | 0.79 | PARP1 (0.47) | DHODHKDM4EHPGDPARP1 | |
| SCHEMBL9492739 | 0.78 | DHODH (0.40) | DHODHKDM4EHPGDPARP1 | |
| SCHEMBL8868621 | 0.73 | KDM4E (0.41) | DHODHKDM4EHPGDPARP1 | |
| SCHEMBL789857 | 0.71 | ABCB11 (0.36) | DHODH | |
| SCHEMBL2512493 | 0.70 | AGTR2 (0.51) | — | |
| SCHEMBL9491813 | 0.68 | DHODH (0.40) | DHODH | |
| Azilsartan SCHEMBL284893 | 0.67 | AGTR2 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243054-A | Hypotensive agents, cardiovascular disorders or nervous system disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |