SCHEMBL949444

SCHEMBL949444

Oc1ccc(C#Cc2ccc(F)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.58
FFAR1 O14842 1/20 0.47
CA12 O43570 2/20 0.46
CA2 P00918 2/20 0.46
CA3 P07451 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA6 P23280 1/20 0.46
GAA P10253 1/20 0.45
GRIN2B Q13224 1/20 0.44
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
GRM5 P41594 2/20 0.42
MEN1 O00255 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GMNN O75496 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4277452 0.88 PTGS1 (0.47) APPFFAR1CA12CA2CA9
SCHEMBL718949 0.86 GRM5 (0.50) APPFFAR1CA12CA2CA9
SCHEMBL7717366 0.86 GRM5 (0.50) APPFFAR1CA12CA2CA9
SCHEMBL10300106 0.86 GRM5 (0.50) APPFFAR1CA12CA2CA9
SCHEMBL14400750 0.86 APP (0.74) APPCA12CA2CA3CA9
SCHEMBL673609 0.86 APP (0.74) APPCA12CA2CA3CA9
SCHEMBL20212084 0.83 GRM5 (0.50) APPFFAR1CA12CA2CA9
Fluoride SCHEMBL31286313 0.83 GRM5 (0.48) APPFFAR1CA12CA2CA9
Charcoal, Activated SCHEMBL31286307 0.83 GRM5 (0.48) APPFFAR1CA12CA2CA9
SCHEMBL78213 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554797-A1 ANTI-COUNTERFEITING LABEL FOR THE AUTHENTICATION OF GOODS Politecnico di Milano (IT) 2025-05-21 EP claimed
WO-2024013693-A1 ANTI-COUNTERFEITING LABEL FOR THE AUTHENTICATION OF GOODS POLITECNICO DI MILANO (IT) 2024-01-18 WO claimed
CN-113105883-B Supermolecule afterglow luminescent compound based on diphenyl acetylene and cyclodextrin, preparation and application 汕头大学 2023-08-18 CN claimed
CN-113105883-A Super-molecular afterglow luminescent compound based on tolane and cyclodextrin, preparation and application thereof 汕头大学 2021-07-13 CN claimed
US-8519080-B2 Crosslinkable prepolymer, its production process and its uses ASAHI GLASS COMPANY, LIMITED (JP) 2013-08-27 US claimed
CN-101454375-B Crosslinkable prepolymer, process for production thereof, and use thereof ASAHI GLASS CO LTD 2012-06-06 CN claimed
CN-100519623-C Fluorinated aromatic polymer and use thereof ASAHI GLASS CO LTD (JP) 2009-07-29 CN claimed
CN-100519624-C Crosslinkable fluoroaromatic prepolymer and use thereof ASAHI GLASS CO LTD (JP) 2009-07-29 CN claimed
WO-2024090559-A1 COMPOSITION FOR CROSSLINKING FLUORORUBBER, AND MOLDED ARTICLE ダイキン工業株式会社 2024-05-02 WO disclosed
CN-113105883-B Supermolecule afterglow luminescent compound based on diphenyl acetylene and cyclodextrin, preparation and application 汕头大学 2023-08-18 CN disclosed
US-11667840-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
CN-114751806-A Diaryl acetylene compound and preparation method thereof 上海泰坦科技股份有限公司 2022-07-15 CN disclosed
CN-113105883-A Super-molecular afterglow luminescent compound based on tolane and cyclodextrin, preparation and application thereof 汕头大学 2021-07-13 CN disclosed
EP-3529331-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-10-07 EP disclosed
EP-1995635-A1 NEGATIVE-TYPE PHOTOSENSITIVE FLUORINATED AROMATIC RESIN COMPOSITION Asahi Glass Company, Limited (JP) 2008-11-26 EP disclosed
US-20060173129-A1 Crosslinkable fluorinated aromatic prepolymer and its uses ASAHI GLASS COMPANY, LIMITED (JP) 2006-08-03 US disclosed
EP-1669389-A1 CROSSLINKABLE FLUOROAROMATIC PREPOLYMER AND USE THEREOF ASAHI GLASS COMPANY LTD. (JP) 2006-06-14 EP disclosed
US-6881811-B2 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY, LIMITED (JP) 2005-04-19 US disclosed
CN-1525988-A Fluorinated aromatic polymer and use thereof ������������ʽ���� 2004-09-01 CN disclosed
US-20040147710-A1 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY LIMITED (JP) 2004-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667840-B2 Liquid-crystalline medium FES, BLM, CXCL12 APP 1021/4885FFAR1 3447/4885CA12 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.