Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656424 | 0.83 | TRPA1 (0.33) | TRPA1MEN1LMNAKMT2A | |
| SCHEMBL9495399 | 0.79 | RARB (0.38) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL9494339 | 0.65 | — | — | |
| SCHEMBL3390707 | 0.65 | RARB (0.44) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL17706525 | 0.62 | ALDH1A1 (0.40) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL14377497 | 0.62 | ALDH1A1 (0.45) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL8610756 | 0.61 | ALDH1A1 (0.38) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL9272007 | 0.61 | MEN1 (0.42) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL1105235 | 0.60 | MAPT (0.41) | TRPA1ACE2PDCD1CD274RARB | |
| SCHEMBL8612375 | 0.60 | ALDH1A1 (0.39) | TRPA1ACE2PDCD1CD274RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268355-A | Naphto(2,1-b)furan structure | FIRMENICH S.A. (CH) | 1993-12-07 | — | — | US | disclosed |