Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494561 | 1.00 | NPSR1 (0.41) | NPSR1GLO1FAAHALDH1A1CYP2D6 | |
| SCHEMBL10454777 | 1.00 | NPSR1 (0.41) | NPSR1GLO1FAAHALDH1A1CYP2D6 | |
| SCHEMBL29117663 | 0.86 | FAAH (0.51) | FAAHALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL22588817 | 0.86 | HCAR2 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRGAA | |
| SCHEMBL28489021 | 0.86 | HCAR2 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRGAA | |
| SCHEMBL9624952 | 0.86 | ALDH1A1 (0.43) | NPSR1GLO1FAAHALDH1A1SOAT1 | |
| SCHEMBL5143636 | 0.85 | FAAH (0.54) | FAAHALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL29117819 | 0.85 | FAAH (0.54) | FAAHALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL29063070 | 0.85 | FAAH (0.54) | FAAHALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL5768191 | 0.85 | FAAH (0.54) | FAAHALDH1A1HSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262561-A | Dehydrobromination of ester, saponification, antiepileptic agents | ELF SANOFI (FR) | 1993-11-16 | — | — | US | disclosed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4965401-A | Process for the preparation of 2-propyl-2-pentenoic acid and its esters | SANOFI (FR) | 1990-10-23 | — | — | US | disclosed |
| EP-0293753-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | disclosed |