Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.48 |
| ▸ | HTR3B | O95264 | 3/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759349 | 0.90 | MAPK1 (0.62) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL9129351 | 0.90 | MAPK1 (0.62) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL31576798 | 0.90 | MAPK1 (0.62) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL29375842 | 0.90 | MAPK1 (0.62) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL27817335 | 0.84 | ALDH1A1 (0.55) | MAPK1TDP1HTR3EHTR3BHTR3A | |
| SCHEMBL10978028 | 0.82 | MAPT (0.61) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL10978025 | 0.82 | MAPT (0.61) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL3282366 | 0.82 | LMNA (0.57) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL3282369 | 0.82 | LMNA (0.57) | MAPK1TDP1TP53HTR3EHTR3B | |
| SCHEMBL11429978 | 0.80 | CYP3A4 (0.58) | MAPK1TDP1TP53HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179223-A | Reacting primary amine, urea and oxime | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |