Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17213603 | 0.90 | KMT2A (0.78) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL11412031 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL6579498 | 0.90 | MAPK1 (0.68) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL11302253 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL2502606 | 0.88 | NPC1 (0.76) | SMN1; SMN2HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL11680494 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL2800153 | 0.88 | ALDH1A1 (0.73) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL14405824 | 0.87 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL2282561 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 | |
| SCHEMBL588524 | 0.86 | HPGD (0.86) | SMN1; SMN2HPGDMAPTCYP2C19ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150306077-A1 | Novel Compositions and Methods for Treating Cancer | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2015-10-29 | — | — | US | disclosed |
| US-9073851-B2 | Compositions and methods for treating cancer | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-23 | — | — | US | disclosed |
| EP-0315112-B1 | NOVEL AMIDE COMPOUNDS | Toyo Boseki Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4912135-A | Benzene ring with amido substitutions in position 1 and 3 | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0315112-A2 | Novel amide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306077-A1 | Novel Compositions and Methods for Treating Cancer | HDGF, HCCS, CCNC | SMN1; SMN2 2523/4885HPGD 321/4885MAPT 1610/4885 |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | HDGF, HCCS, CCNC | SMN1; SMN2 2523/4885HPGD 321/4885MAPT 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.