Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248995 | 0.89 | KMT2A (0.41) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9494592 | 0.82 | NPC1 (0.43) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9495346 | 0.81 | TDP1 (0.35) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9494505 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9497255 | 0.78 | MAPT (0.46) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL9495088 | 0.77 | RAB9A (0.47) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9498592 | 0.74 | NPC1 (0.41) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9494243 | 0.72 | — | — | |
| SCHEMBL5257296 | 0.71 | MEN1 (0.42) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9495354 | 0.71 | HTT (0.44) | HTTALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |