Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257296 | 0.88 | MEN1 (0.42) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL9495346 | 0.86 | TDP1 (0.35) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL9498592 | 0.84 | NPC1 (0.41) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL9494505 | 0.83 | KMT2A (0.46) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9495360 | 0.82 | HTT (0.44) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL9497255 | 0.82 | MAPT (0.46) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL9495088 | 0.81 | RAB9A (0.47) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL9494243 | 0.76 | — | — | |
| SCHEMBL9499235 | 0.74 | MEN1 (0.39) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9496926 | 0.72 | POLB (0.43) | NPC1RAB9AKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |