Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495397 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL9495401 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL10887977 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL10887982 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL11236160 | 0.71 | GAA (0.38) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL9492968 | 0.70 | — | — | |
| SCHEMBL10721434 | 0.69 | LMNA (0.42) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL10721429 | 0.69 | LMNA (0.42) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL10880739 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL10880745 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | claimed |
| US-5177091-A | Rheumatic disorders | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |