SCHEMBL9495463

SCHEMBL9495463

CC(C)CC(C(=O)O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.43
ESR2 Q92731 6/20 0.43
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 2/20 0.43
BLM P54132 1/20 0.40
CA2 P00918 1/20 0.39
CAMK2A Q9UQM7 1/20 0.39
LMNA P02545 1/20 0.39
TYR P14679 1/20 0.39
AR P10275 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4192907 0.79 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL890797 0.76 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL4214180 0.75 CA2 (0.48) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL27965739 0.74 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL9472085 0.74 ESR1 (0.58) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL51337 0.73 ESR1 (0.59) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL3120824 0.73 ESR1 (0.58) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL52004 0.72 ESR1 (0.50) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL8409614 0.72 ESR2 (0.53) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL9562152 0.72 ESR1 (0.62) ESR1ESR2CYP3A4ALDH1A1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP claimed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US claimed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US disclosed
EP-0189760-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1989-07-19 EP disclosed
US-4833121-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed