Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500778 | 0.90 | TEAD1 (0.38) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| SCHEMBL9569701 | 0.88 | RORC (0.45) | TEAD1TEAD4TEAD2TEAD3P2RY1 | |
| SCHEMBL9495320 | 0.88 | SLC5A1 (0.47) | TEAD1TEAD4TEAD2TEAD3SCN9A | |
| SCHEMBL30212108 | 0.86 | RORC (0.45) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| SCHEMBL8830041 | 0.86 | RORC (0.45) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| SCHEMBL30626343 | 0.86 | TEAD1 (0.40) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| SCHEMBL26074914 | 0.86 | TEAD1 (0.40) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| Potassium SCHEMBL10479127 | 0.85 | RORC (0.44) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| SCHEMBL8830115 | 0.83 | RORC (0.44) | TEAD1TEAD4TEAD2TEAD3ABCB1 | |
| SCHEMBL30311004 | 0.82 | TP53 (0.44) | TEAD1TEAD4TEAD2TEAD3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320793-B1 | CINNOLINE DERIVATIVE, PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0320782-B1 | PLANT MALE STERILANT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0320793-A2 | Cinnoline derivative, process for preparing the same and herbicidal composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-21 | — | — | EP | disclosed |