Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495490 | 0.88 | TEAD1 (0.39) | RORCTP53TEAD1TEAD4TEAD2 | |
| SCHEMBL8636360 | 0.87 | RORC (0.46) | RORCALDH1A1TP53HCRTR1HCRTR2 | |
| SCHEMBL8637313 | 0.87 | RORC (0.52) | RORCALDH1A1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL30212108 | 0.86 | RORC (0.45) | RORCTP53TEAD1TEAD4TEAD2 | |
| SCHEMBL8830041 | 0.86 | RORC (0.45) | RORCTP53TEAD1TEAD4TEAD2 | |
| SCHEMBL8641097 | 0.85 | RORC (0.49) | RORCALDH1A1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL30311004 | 0.85 | TP53 (0.44) | TP53TEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL26074779 | 0.85 | TP53 (0.44) | TP53TEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL8830115 | 0.85 | RORC (0.44) | RORCTP53TEAD1TEAD4TEAD2 | |
| Potassium SCHEMBL10479127 | 0.85 | RORC (0.44) | RORCTP53TEAD1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530063-A1 | Pollen suppressant for dicotyledon plants comprising a 5-oxy-substituted cinnoline | ORSAN (FR) | 1993-03-03 | — | — | EP | disclosed |
| EP-0530064-A1 | Pollen suppressant for Liliopsida plants comprising a 5-oxy-substituted cinnoline | HYBRINOVA (FR) | 1993-03-03 | — | — | EP | disclosed |
| US-5129940-A | Antifertility agents for Liliopsida | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |