Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495798 | 1.00 | FFAR1 (0.41) | FFAR1KCNH2LMNASIGMAR1FFAR4 | |
| SCHEMBL21246894 | 0.90 | FFAR1 (0.47) | FFAR1KCNH2LMNAFFAR4SLC6A2 | |
| SCHEMBL29306017 | 0.81 | FFAR1 (0.41) | FFAR1KCNH2LMNAFFAR4GRM5 | |
| SCHEMBL9497272 | 0.81 | FFAR1 (0.41) | FFAR1FFAR4GRM5 | |
| SCHEMBL9497279 | 0.81 | FFAR1 (0.41) | FFAR1FFAR4GRM5 | |
| SCHEMBL22622902 | 0.81 | GRM5 (0.44) | FFAR1KCNH2FFAR4GRM5 | |
| SCHEMBL9498077 | 0.81 | FFAR1 (0.42) | FFAR1KCNH2LMNAFFAR4SLC6A2 | |
| SCHEMBL9498083 | 0.81 | FFAR1 (0.42) | FFAR1KCNH2LMNAFFAR4SLC6A2 | |
| SCHEMBL9500527 | 0.78 | FFAR1 (0.40) | FFAR1KCNH2FFAR4SLC6A2SLC6A4 | |
| SCHEMBL9500523 | 0.78 | FFAR1 (0.40) | FFAR1KCNH2FFAR4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |