Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498083 | 1.00 | FFAR1 (0.42) | FFAR1FFAR4KCNH2PGK1SLC6A2 | |
| SCHEMBL9496202 | 0.91 | FFAR1 (0.47) | FFAR1FFAR4KCNH2PGK1ACACB | |
| SCHEMBL9854903 | 0.91 | FFAR1 (0.47) | FFAR1FFAR4KCNH2PGK1ACACB | |
| SCHEMBL9500523 | 0.87 | FFAR1 (0.40) | FFAR1FFAR4KCNH2PGK1SLC6A2 | |
| SCHEMBL9500527 | 0.87 | FFAR1 (0.40) | FFAR1FFAR4KCNH2PGK1SLC6A2 | |
| SCHEMBL21246894 | 0.86 | FFAR1 (0.47) | FFAR1FFAR4KCNH2SLC6A2SLC6A4 | |
| SCHEMBL9498796 | 0.84 | KCNH2 (0.39) | FFAR1FFAR4KCNH2SLC6A3LMNA | |
| SCHEMBL9498804 | 0.84 | KCNH2 (0.39) | FFAR1FFAR4KCNH2SLC6A3LMNA | |
| SCHEMBL9497422 | 0.83 | FFAR1 (0.42) | FFAR1FFAR4ACACBGRM5 | |
| SCHEMBL9497432 | 0.83 | FFAR1 (0.42) | FFAR1FFAR4ACACBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |