Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994057 | 1.00 | ADORA1 (0.77) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL1994061 | 1.00 | ADORA1 (0.77) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL4134920 | 1.00 | ADORA1 (0.77) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL9142291 | 1.00 | ADORA1 (0.77) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL17921080 | 0.90 | ADORA3 (0.72) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL8820476 | 0.90 | LMNA (0.75) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL8820466 | 0.90 | LMNA (0.75) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL5389231 | 0.89 | LMNA (0.71) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL6259651 | 0.89 | LMNA (0.71) | ADORA1ADORA3LMNATP53ADORA2A | |
| SCHEMBL6259647 | 0.89 | LMNA (0.71) | ADORA1ADORA3LMNATP53ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253962-B1 | USE OF ADENOSINE DERIVATIVES AS ANTI-DEMENTIA AGENTS | HOECHST JAPAN LIMITED (JP) | 1993-03-24 | — | — | EP | disclosed |