Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424854 | 0.86 | CA12 (0.48) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL27418562 | 0.83 | CA12 (0.46) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL10326300 | 0.81 | CA12 (0.44) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1972478 | 0.81 | CA12 (0.44) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL18346854 | 0.81 | ALDH1A1 (0.49) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3291445 | 0.81 | CA12 (0.44) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL28847614 | 0.81 | CA12 (0.45) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL20377455 | 0.80 | CA12 (0.43) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL5179763 | 0.80 | CA12 (0.43) | CA12CA9BRD4BRPF1KAT2B | |
| Water SCHEMBL28440490 | 0.80 | CA12 (0.44) | CA12CA9BRD4BRPF1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924243-A | Quinoline derivative, pharmaceutical composition and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | disclosed |
| EP-3022202-A1 | AUTOTAXIN INHIBITORS COMPRISING A HETEROAROMATIC RING-BENZYL-AMIDE-CYCLE CORE | Novartis AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| EP-3022201-A1 | AUTOTAXIN INHIBITORS | Novartis AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| US-20150203467-A1 | METHOD FOR PRODUCING LINEAR AND/OR CYCLIC CARBONATE ESTERS | BAYER MATERIALSCIENCE AG (DE) | 2015-07-23 | — | — | US | disclosed |
| WO-2015008230-A1 | AUTOTAXIN INHIBITORS COMPRISING A HETEROAROMATIC RING-BENZYL-AMIDE-CYCLE CORE | NOVARTIS AG (CH) | 2015-01-22 | — | — | WO | disclosed |
| WO-2015008229-A1 | Autotaxin inhibitors | NOVARTIS AG (CH) | 2015-01-22 | — | — | WO | disclosed |
| EP-0240859-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4761403-A | QUINOLONE DERIVATIVES | ABBOTT LABORATORIES (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0240859-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1987-10-14 | — | — | EP | disclosed |
| US-3953456-A | ADRENERGIC BLOCKING AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203467-A1 | METHOD FOR PRODUCING LINEAR AND/OR CYCLIC CARBONATE ESTERS | MSMO1, CA4, ME1 | CA12 12/4885CA9 18/4885BRD4 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.