Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250434 | 0.90 | PDE4B (0.44) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL9495132 | 0.80 | LDHA (0.43) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL5251146 | 0.79 | LDHA (0.59) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL5249954 | 0.76 | HPGD (0.64) | HPGDCYP2C19CYP1A2LDHAMAPT | |
| SCHEMBL8136988 | 0.76 | HPGD (0.62) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL11366776 | 0.76 | HPGD (0.62) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL5249899 | 0.76 | ALDH1A1 (0.46) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL29837153 | 0.76 | LDHA (0.48) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL5251469 | 0.75 | KMT2A (0.55) | HPGDCYP2C19CYP1A2CYP2C9LDHA | |
| SCHEMBL9494568 | 0.75 | TP53 (0.53) | HPGDCYP2C19CYP1A2CYP2C9LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |