Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496751 | 0.86 | MAPT (0.40) | MAPTAHRHTTADRB3ADRB2 | |
| SCHEMBL9497412 | 0.82 | CES2 (0.40) | MAPTMEN1KMT2ACYP3A4ADORA3 | |
| SCHEMBL9498269 | 0.79 | MEN1 (0.40) | MAPTAHRTSHRNPC1RAB9A | |
| SCHEMBL9497155 | 0.78 | CES2 (0.45) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8035724 | 0.75 | MAPT (0.71) | MAPTJAK2JAK1TYK2AHR | |
| SCHEMBL11271609 | 0.75 | MAPT (0.68) | MAPTJAK2JAK1TYK2AHR | |
| SCHEMBL11298296 | 0.75 | MAPT (0.71) | MAPTJAK2JAK1TYK2AHR | |
| SCHEMBL11271604 | 0.75 | MAPT (0.68) | MAPTJAK2JAK1TYK2AHR | |
| SCHEMBL21829067 | 0.74 | MAPT (0.71) | MAPTJAK2JAK1TYK2AHR | |
| SCHEMBL9498258 | 0.74 | CES1 (0.44) | MAPTSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212197-A | Agriculture | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-05-18 | — | — | US | disclosed |
| EP-0508527-A1 | New fungicidally active pyrazole compounds | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1992-10-14 | — | — | EP | disclosed |