Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496408 | 0.86 | MAPT (0.57) | MAPTAHRADRB2ADRB1ADRB3 | |
| SCHEMBL9498269 | 0.82 | MEN1 (0.40) | MAPTAHRCA12CA1CA2 | |
| SCHEMBL9497412 | 0.77 | CES2 (0.40) | MAPT | |
| SCHEMBL9497155 | 0.76 | CES2 (0.45) | MAPTHTT | |
| SCHEMBL9499133 | 0.72 | CYP3A4 (0.40) | MAPT | |
| SCHEMBL9498258 | 0.72 | CES1 (0.44) | MAPT | |
| SCHEMBL28457349 | 0.64 | — | — | |
| SCHEMBL21851372 | 0.63 | MAPT (0.48) | MAPTAHRADRB2ADRB1ADRB3 | |
| SCHEMBL9187076 | 0.63 | HPGD (0.49) | MAPT | |
| SCHEMBL11546192 | 0.62 | AHR (0.47) | MAPTAHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212197-A | Agriculture | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-05-18 | — | — | US | disclosed |
| EP-0508527-A1 | New fungicidally active pyrazole compounds | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1992-10-14 | — | — | EP | disclosed |