Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 6/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496425 | 1.00 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL7213672 | 1.00 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL10579044 | 1.00 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL260012 | 0.84 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL259510 | 0.77 | KIF11 (0.37) | KIF11MEN1KMT2A | |
| SCHEMBL6376528 | 0.76 | KMT2A (0.36) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL10515799 | 0.75 | KIF11 (0.43) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL10515519 | 0.75 | KIF11 (0.43) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL10808189 | 0.72 | TYMP (0.49) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL9843712 | 0.72 | TYMP (0.49) | KIF11MEN1KMT2ATYMPSLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5241069-A | Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives | GLAXO INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0487658-A4 | SYNTHESIS OF PURINE SUBSTITUTED CYCLOPENTENE DERIVATIVES | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0489876-A4 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | — | 1992-09-02 | — | — | EP | disclosed |
| US-5126452-A | SYNTHESIS OF PURINE SUBSTITUTED CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0489876-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0487658-A1 | SYNTHESIS OF PURINE SUBSTITUTED CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-03 | — | — | EP | disclosed |
| WO-1991015490-A1 | SYNTHESIS OF PURINE SUBSTITUTED CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-17 | — | — | WO | disclosed |
| WO-1991015447-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-17 | — | — | WO | disclosed |
| US-5057630-A | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-15 | — | — | US | disclosed |
| US-4950758-A | ANTIVIRAL AND ANTITUMOR AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-08-21 | — | — | US | disclosed |