Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 7/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515799 | 1.00 | KIF11 (0.43) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL1045676 | 0.85 | SLC6A1 (0.38) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL2380764 | 0.84 | KIF11 (0.42) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL99028 | 0.84 | KIF11 (0.42) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL18349616 | 0.79 | SLC6A11 (0.45) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL11499543 | 0.76 | KIF11 (0.44) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL17548308 | 0.76 | MEN1 (0.38) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL9496425 | 0.75 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL10579044 | 0.75 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 | |
| SCHEMBL9496419 | 0.75 | KIF11 (0.40) | KIF11MEN1KMT2ATYMPSLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330992-A2 | Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them | Nippon Kayaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |