Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335643 | 0.86 | MTNR1A (0.81) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL55299 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL2351965 | 0.77 | MTNR1A (0.84) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL2597485 | 0.77 | MTNR1A (0.84) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL30089783 | 0.77 | MTNR1A (0.84) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7332063 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7332053 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7333054 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7333056 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL10447045 | 0.75 | MTNR1A (0.70) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532398-A1 | N-(4,7-dimethoxyindan-2-yle)-1-(phenylcarbonyl)-N-propyle-piperidine-4-methane amines, their preparation and their therapeutical application | SYNTHELABO (FR) | 1993-03-17 | — | — | EP | claimed |
| JP-5201978-A | — | — | None | — | — | JP | disclosed |
| JP-H05201978-A | N-(4,7-DIMETHOXY-2-INDANYL)-1-(PHENYLCARBONYL)-N-PROPYL-4-PIRERIDINE METHANEAMINE DERIVATIVE, ITS PREPARATION AND ITS APPLICATION TO PHARMACEUTICALS | SYNTHELABO SA | 1993-08-10 | — | — | JP | disclosed |
| EP-0532398-A1 | N-(4,7-dimethoxyindan-2-yle)-1-(phenylcarbonyl)-N-propyle-piperidine-4-methane amines, their preparation and their therapeutical application | SYNTHELABO (FR) | 1993-03-17 | — | — | EP | disclosed |