Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15064314 | 0.85 | CNR2 (1.00) | CNR2POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL15087599 | 0.84 | CNR2 (0.97) | CNR2POLBMEN1KMT2ACNR1 | |
| SCHEMBL30444477 | 0.82 | CNR2 (0.68) | CNR2POLBMEN1KMT2A | |
| SCHEMBL31661673 | 0.81 | CNR2 (0.72) | CNR2POLBMEN1KMT2A | |
| SCHEMBL1856691 | 0.81 | CNR2 (0.72) | CNR2POLBMEN1KMT2ACNR1 | |
| SCHEMBL8695595 | 0.81 | CNR2 (0.72) | CNR2POLBMEN1KMT2A | |
| SCHEMBL1852549 | 0.81 | CNR2 (0.72) | CNR2POLBMEN1KMT2ACNR1 | |
| SCHEMBL15064610 | 0.80 | CNR2 (1.00) | CNR2POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL31616456 | 0.80 | CNR2 (0.70) | CNR2POLBMEN1KMT2ACNR1 | |
| SCHEMBL4368421 | 0.79 | CTSL (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531080-A2 | Peptide inhibitors of human papilloma virus protein binding to retinoblastoma gene protein | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0412762-A2 | Peptide inhibitors of human papilloma virus protein binding to retinoblastoma gene proteins | MERCK & CO. INC. (US) | 1991-02-13 | — | — | EP | disclosed |