Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495959 | 0.91 | HPGD (0.32) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL9523542 | 0.86 | MAPT (0.35) | HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL9521572 | 0.85 | LMNA (0.34) | HPGDSMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL9494830 | 0.83 | NOTUM (0.38) | HPGDSMN1; SMN2PKML3MBTL1 | |
| SCHEMBL9495601 | 0.83 | TDP1 (0.39) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL9522926 | 0.81 | FNTA (0.38) | NPC1HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL9796398 | 0.81 | LMNA (0.34) | HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL9796159 | 0.80 | BAZ2B (0.34) | HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL9494826 | 0.78 | CA12 (0.39) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL9495723 | 0.77 | CA12 (0.32) | CA12CA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344232-B1 | 3-ARYLURACILS FOR KILLING WEEDS | CIBA-GEIGY AG (CH) | 1993-03-24 | — | — | EP | disclosed |
| US-5041156-A | 3-aryluracils for the control of weeds | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |