Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.38 |
| ▸ | FNTB | P49356 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523542 | 0.86 | MAPT (0.35) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL9521572 | 0.84 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9494830 | 0.82 | NOTUM (0.38) | HPGDSMN1; SMN2 | |
| SCHEMBL9497433 | 0.81 | CA12 (0.39) | LMNAMAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL9796159 | 0.81 | BAZ2B (0.34) | LMNAMAPTHPGDSMN1; SMN2BAZ2B | |
| SCHEMBL9796398 | 0.80 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2BAZ2B | |
| SCHEMBL9495959 | 0.80 | HPGD (0.32) | LMNAMAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL9877333 | 0.76 | HPGD (0.44) | LMNAMAPTHPGDNPC1ATM | |
| SCHEMBL9519617 | 0.73 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2BAZ2B | |
| SCHEMBL9468816 | 0.73 | NPC1 (0.37) | FNTAFNTBLMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |