Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941279 | 0.98 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL10941285 | 0.98 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL10941293 | 0.98 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL9499529 | 0.98 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11749810 | 0.94 | ALDH1A1 (0.33) | CYP1A2CYP2D6CYP2C19ALDH1A1KDM4E | |
| SCHEMBL9500775 | 0.94 | — | — | |
| SCHEMBL7057550 | 0.90 | TSHR (0.38) | CYP1A2CYP2C19ALDH1A1HPGDTSHR | |
| SCHEMBL16544481 | 0.89 | KDM4E (0.31) | KDM4EMAPT | |
| SCHEMBL11699138 | 0.88 | LTA4H (0.37) | HPGDTSHRMEN1KMT2ARAB9A | |
| SCHEMBL6160683 | 0.88 | TSHR (0.40) | ALDH1A1HPGDTSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4236023-A | Preparation of unsaturated monoesters by the catalytic oxidative carbonylation of diolefins with an enol ether or 1-alkoxycycloalkene | ATLANTIC RICHFIELD COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| US-4166913-A | COMPOUNDS OF PLATINUM GROUP AND OF COPPER OR IRON AS CATALYSTS | ATLANTIC RICHFIELD COMPANY (US) | 1979-09-04 | — | — | US | claimed |
| EP-0272110-B1 | ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0272110-A2 | Erythromycin a derivatives and method for the preparation of the same | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4001303-A | BORON COMPOUND; COMPOUNDS, 5; COMPOUNDS, 6; CATALYSTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |