Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9795405 | 0.88 | PDE5A (0.34) | RECQLESR2DPP4 | |
| SCHEMBL9501592 | 0.86 | RECQL (0.36) | RECQLCA12CA1CA2CA4 | |
| SCHEMBL2011680 | 0.80 | FAAH (0.52) | RECQLCA12CA1CA2CA4 | |
| SCHEMBL9501589 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL20113585 | 0.78 | FAAH (0.55) | RECQLGAAESR2TSHR | |
| SCHEMBL9497957 | 0.78 | TSHR (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9500025 | 0.77 | TSHR (0.39) | RECQLCA12CA1CA2CA4 | |
| SCHEMBL2013185 | 0.76 | ESR2 (0.39) | RECQLCA12CA1CA2CA4 | |
| SCHEMBL18115167 | 0.75 | EPHX2 (0.38) | RECQLCA12CA1CA2CA9 | |
| Fumaric Acid SCHEMBL9795500 | 0.75 | PDE5A (0.33) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0367019-A1 | Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds | Roche Diagnostics GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |