Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127154 | 0.80 | DAO (0.43) | KDM4EDAOKMT2ASLC22A12HTT | |
| SCHEMBL6382774 | 0.78 | DAO (0.65) | KDM4EDAOMEN1KMT2APOLB | |
| SCHEMBL7163743 | 0.77 | KDM4E (0.52) | KDM4EDAOMEN1KMT2ALMNA | |
| SCHEMBL10677691 | 0.77 | KDM4E (0.52) | KDM4EDAOMEN1KMT2ALMNA | |
| SCHEMBL28165616 | 0.77 | DAO (0.62) | KDM4EDAOMEN1KMT2ALMNA | |
| SCHEMBL9499552 | 0.74 | DAO (0.51) | KDM4EDAOKMT2AFEN1 | |
| SCHEMBL9849536 | 0.74 | DAO (0.61) | KDM4EDAOLMNACCR2AHR | |
| SCHEMBL28325706 | 0.73 | LMNA (0.48) | KDM4EMEN1KMT2AHTTLMNA | |
| SCHEMBL9496407 | 0.73 | DAO (0.47) | KDM4EDAOMEN1KMT2AHTT | |
| SCHEMBL9849401 | 0.73 | DAO (0.50) | KDM4EDAOMEN1KMT2ACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240859-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-28 | — | — | EP | disclosed |